公开(公告)号：US20250095772A1

公开(公告)日：2025-03-20

申请号：US18579798

申请日：2023-06-05

Applicant: SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Hongchao JI ,  Soonheng TAN

IPC: G16B15/30 ,  G16B40/20

Abstract: The present application provides a method for improving a throughput of compound-protein interaction experiments. In the method of this application, multiple compounds to be tested are composed into multiple mixture systems according to a certain mixing rule, and corresponding relationships between abilities of the compounds to be tested to interact with the protein target and the mixture systems are established, and then the target protein corresponding to the compound to be tested is analyzed in a high-throughput manner. The analysis method of the present application can increase a detection throughput of the existing compound to be tested-target protein experiments by more than 10 times, while saving more than 90% of the experimental cost and time, significantly reducing the cost of manpower, time and experimental consumables, which has significant economic significance.