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1.
公开(公告)号:US10294224B2
公开(公告)日:2019-05-21
申请号:US15532281
申请日:2015-12-04
IPC分类号: C07D471/08 , A61K9/19 , A61K31/439 , A61K9/00 , A61K47/02
摘要: A process for producing crystals of a compound represented by the following formula (I): by crystallizing the compound from an aqueous solution containing the compound and an inorganic salt, such as sodium chloride. Such crystals can be subjected to lyophilization to provide a lyophilized composition having a desirable storage stability.
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公开(公告)号:US11117895B2
公开(公告)日:2021-09-14
申请号:US16297550
申请日:2019-03-08
IPC分类号: C07D471/08 , A61K9/19 , A61K31/439 , A61K47/02 , A61K9/00
摘要: A process for producing crystals of a compound represented by the following formula (I): by crystallizing the compound from an aqueous solution containing the compound and an inorganic salt, such as sodium chloride. Such crystals can be subjected to lyophilization to provide a lyophilized composition having a desirable storage stability.
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