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    Thermal cycler systems and methods of use
    1.
    发明授权
    Thermal cycler systems and methods of use 有权

    公开(公告)号：US10471432B2

    公开(公告)日：2019-11-12

    申请号：US15387614

    申请日：2016-12-21

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Zeqi Tan ,  Wuh Ken Loh ,  Siew Yin Lee ,  Kuan Moon (Bernard) Boo

    IPC: B01L7/00 ,  B01L9/00

    Abstract: A thermal cycler system for use with a sample holder configured to receive a plurality of samples includes a sample block having an upstanding peripheral side wall and being configured to receive the sample holder and an adaptor having an upstanding peripheral side wall configured to be positioned about the peripheral side wall of the sample block. When the peripheral side wall of the adaptor is positioned about the peripheral side wall of the sample block and the sample holder is received in the sample block, the peripheral side wall of the adaptor extends in an upward direction toward the sample holder.

    Biological analysis devices and systems
    3.
    发明授权
    Biological analysis devices and systems 有权

    公开(公告)号：US12140544B2

    公开(公告)日：2024-11-12

    申请号：US18308177

    申请日：2023-04-27

    Applicant: LIFE TECHNOLOGIES HOLDINGS PTE LIMITED ,  LIFE TECHNOLOGIES CORPORATION

    Inventor： Ming Song Chen ,  Chee Woei Chong ,  Wuh Ken Loh ,  Wern Yuh Foo ,  Kuan Moon Boo ,  Norbert Leclerc ,  Kristina Uhlendorf ,  Reiner Koellner ,  Torsten Fuchs ,  Stefan Breitfelder

    IPC: G01N21/64

    Abstract: A biological analysis system can include an excitation module and an emission module. The excitation module can include a collimator element for receiving excitation light from the excitation light source and transmitting collimated excitation light in a first direction, and a plurality of excitation mirrors arrayed along the excitation light path, each excitation mirror disposed at an acute angle relative to the first direction and configured to reflect collimated excitation light along a second direction. The emission module can be positioned to receive excitation light transmitted along the second direction and can include a sample block comprising a plurality of sample receptacles positioned to receive a beam of collimated excitation light, and a plurality of photodetectors configured to receive emission light transmitted from a respective sample receptacle in a direction transverse to the second direction of the excitation light path.

    Systems and methods for biological analysis
    6.
    发明授权
    Systems and methods for biological analysis 有权

    公开(公告)号：US11583862B2

    公开(公告)日：2023-02-21

    申请号：US15266943

    申请日：2016-09-15

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Kuan Moon Boo ,  Wei Fuh Teo ,  Wuh Ken Loh ,  Zeqi Tan ,  Siew Yin Lee

    IPC: B01L7/00 ,  B01L9/00 ,  B01L99/00 ,  F25B21/04

    Abstract: A thermal block assembly for use in a biological analysis system includes a sample block, a heating and cooling element, a heat sink including a surface, the surface including a plurality of projections for engaging the heating and cooling element to hold the heating and cooling element on the heat sink. A thermal block assembly for use in a biological analysis system includes a heating and cooling element, a sample block including a lower surface configured to be thermally coupled to the heating and cooling element, one or more temperature sensors configured to extend through the one or more slots of the lower surface of the sample block, and one or more thermal pads between the one or more temperature sensors and heating and cooling element.

    Thermal cycler cover
    8.
    发明授权
    Thermal cycler cover 有权

    公开(公告)号：US10239059B2

    公开(公告)日：2019-03-26

    申请号：US14778106

    申请日：2014-02-14

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Tiong Han Toh ,  Wuh Ken Loh ,  Kuan Moon Boo ,  Sandro Klein ,  Daniel Welsh

    IPC: B01L7/00

    Abstract: In one aspect, a thermal cycler system is disclosed. The thermal cycler can be comprised of a device housing and a cover that is operably connected to the device housing. The cover can include a handle portion, a device lid portion, a sample block platen, and a link bar. The device lid portion is attached to the proximal side of the handle portion with a first pin. The sample block platen is operably connected to the handle portion such that the sample block platen is positioned against the sample block when the handle portion is flush with the device lid portion and the cover is in a closed position. The link bar is pivotably connected to the device housing at a first terminal end portion and a second pin at an opposite second terminal end portion, wherein the handle portion is elevated away from the device lid portion before the cover is moved to an open position.

    Thermal cycler systems and methods of use
    10.
    发明授权
    Thermal cycler systems and methods of use 有权

    公开(公告)号：US11548007B2

    公开(公告)日：2023-01-10

    申请号：US16590459

    申请日：2019-10-02

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Zeqi Tan ,  Wuh Ken Loh ,  Siew Yin Lee ,  Kuan Moon (Bernard) Boo

    IPC: B01L7/00 ,  B01L9/00

    Abstract: A thermal cycler system for use with a sample holder configured to receive a plurality of samples includes a sample block having an upstanding peripheral side wall and being configured to receive the sample holder and an adaptor having an upstanding peripheral side wall configured to be positioned about the peripheral side wall of the sample block. When the peripheral side wall of the adaptor is positioned about the peripheral side wall of the sample block and the sample holder is received in the sample block, the peripheral side wall of the adaptor extends in an upward direction toward the sample holder.

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