PRIMERS, METHODS AND KITS FOR DETECTING KILLER-CELL IMMUNOGLOBULIN-LIKE RECEPTOR ALLELES
    1.
    发明申请
    PRIMERS, METHODS AND KITS FOR DETECTING KILLER-CELL IMMUNOGLOBULIN-LIKE RECEPTOR ALLELES 审中-公开
    用于检测杀伤细胞类免疫球蛋白样受体相关基因的方法和试剂盒

    公开(公告)号:US20150056621A1

    公开(公告)日:2015-02-26

    申请号:US14477293

    申请日:2014-09-04

    CPC classification number: C12Q1/6883 C12Q1/6876 C12Q2600/16

    Abstract: Embodiments of the present invention describe primer pairs, methods and kits for identifying and/or detecting killer-cell immunoglobulin-like receptor (KIR) alleles. The present primer sets include one or more primer pairs that can produce amplicons specific for an individual KIR allele and that are less than 1000 bp in size. Additionally, the primer sets can target intra-exon and/or extracellular domains of KIR alleles for amplification.

    Abstract translation: 本发明的实施方案描述了用于鉴定和/或检测杀伤细胞免疫球蛋白样受体(KIR)等位基因的引物对,方法和试剂盒。 本发明的引物组包括一个或多个引物对,其可以产生对个体KIR等位基因特异性且小于1000bp的扩增子。 此外,引物组可以靶向用于扩增的KIR等位基因的外显子和/或细胞外结构域。

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