专利检索 ap:("Intercept Pharmaceuticals, Inc.") AND inv:"Gabriel Galvin" 第 1 页

1.

发明授权
Methods and intermediates for the preparation of bile acid derivatives 有权

公开(公告)号：US11066437B2

公开(公告)日：2021-07-20

申请号：US16016486

申请日：2018-06-22

申请人： Intercept Pharmaceuticals, Inc.

发明人： Roberto Pellicciari , Antimo Gioiello , Gabriel Galvin , Ronald D. Lewis, II , Mathew Yanik , Myoung Goo Kim , Frederik Ronald Leusink , Bartjan Koning , Thomas Hensel

IPC分类号： C07J9/00 , C07J31/00

摘要： The present disclosure relates to methods and novel intermediates useful in the preparation of a compound of formula I or pharmaceutically acceptable salt, hydrate, solvate or amino acid, sulfate or glucuronide conjugate, or prodrug thereof, comprising the step of reacting a compound of formula I-4 with a halogenating reagent to provide a compound of formula I-5a

2.

发明授权
Isotopically labeled bile acid derivatives 有权

公开(公告)号：US11472831B2

公开(公告)日：2022-10-18

申请号：US16632093

申请日：2018-07-23

申请人： Intercept Pharmaceuticals, Inc.

发明人： Gabriel Galvin , Kevin Schaab , Mathew Yanik

IPC分类号： C07J41/00 , C07J9/00 , C07J17/00

摘要： The present application relates to isotopically labeled compounds of Formula I and methods of preparation and use thereof.

3.

发明申请
METHODS AND INTERMEDIATES FOR THE PREPARATION OF BILE ACID DERIVATIVES 审中-公开

公开(公告)号：US20180371009A1

公开(公告)日：2018-12-27

申请号：US16016486

申请日：2018-06-22

申请人： Intercept Pharmaceuticals, Inc.

发明人： Roberto Pellicciari , Antimo Gioiello , Gabriel Galvin , Ronald D Lewis , Mathew Yanik , Myoung Goo Kim , Fred Leusink , Bartjan Koning , Thomas Hensel

IPC分类号： C07J9/00

摘要： The present disclosure relates to methods and novel intermediates useful in the preparation of a compound of formula I or pharmaceutically acceptable salt, hydrate, solvate or amino acid, sulfate or glucuronide conjugate, or prodrug thereof.