公开(公告)号：US20140179620A1

公开(公告)日：2014-06-26

申请号：US13964861

申请日：2013-08-12

Applicant: GENENTECH, INC.

Inventor： Alexander R. Abbas ,  Hilary Clark ,  Lauri Diehl ,  Charles Lees ,  Colin L. Noble ,  Jack Satsangi

IPC: C12Q1/68 ,  G01N33/564

CPC classification number: G01N33/564 ,  A61K31/56 ,  A61K31/606 ,  C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/172

Abstract: The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.

Abstract translation: 本发明涉及炎症性肠病发病机理的基因表达谱的方法，其中测定来自一个或多个IBD标记物的哺乳动物受试者相对于对照的测试样品中的差异表达，其中测试样品中的差异表达 指示获得测试样品的哺乳动物受试者中的IBD。

公开(公告)号：US20140154275A1

公开(公告)日：2014-06-05

申请号：US14020628

申请日：2013-09-06

Applicant: GENENTECH, INC.

Inventor： Alexander R. Abbas ,  Hilary Clark ,  Lauri Diehl ,  Charles Lees ,  Colin L. Noble ,  Jack Satsangi

IPC: C12Q1/68

CPC classification number: C12Q1/6883 ,  C12Q2600/158

Abstract: The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.

Abstract translation: 本发明涉及炎症性肠病发病机理的基因表达谱的方法，其中测定来自一个或多个IBD标记物的哺乳动物受试者相对于对照的测试样品中的差异表达，其中测试样品中的差异表达 指示获得测试样品的哺乳动物受试者中的IBD。