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公开(公告)号:US20210172932A1
公开(公告)日:2021-06-10
申请号:US17177414
申请日:2021-02-17
Applicant: GENENTECH, INC.
Inventor: Shan CHUNG , Van Hong NGUYEN , An SONG
Abstract: The present disclosure relates to methods and compositions useful for measuring the transcytosis of a molecule. In particular, the present disclosure relates to in vitro receptor-dependent transcytosis assays for evaluating the clearance rates of therapeutic antibody molecules and Fc-fusion proteins in humans and animals.