公开(公告)号：US20220339155A1

公开(公告)日：2022-10-27

申请号：US17632963

申请日：2020-08-20

Applicant: City of Hope

Inventor： Jianjun Chen ,  Xiaolan Deng ,  Li Han ,  Hongzhi Li ,  Rui Su

IPC: A61K31/519

Abstract: The disclosure provides, inter alia, METTL16 inhibitors and methods of treating cancers that overexpress METTL16.

公开(公告)号：US20220370434A1

公开(公告)日：2022-11-24

申请号：US17627059

申请日：2020-07-23

Applicant: City of Hope

Inventor： Jianjun Chen ,  Rui Su ,  David Horne ,  Xiaolan Deng ,  Hongzhi Li ,  Jun Xie

IPC: A61K31/47 ,  A61P35/02 ,  A61K31/4178 ,  A61K31/7068 ,  A61K31/704 ,  A61K31/495 ,  A61K45/06 ,  C07D233/52 ,  C07D403/14 ,  C07D215/52 ,  C07D219/04 ,  A61K31/497 ,  A61K31/473

Abstract: Provided, inter alia, are methods and compositions for treating FTO-mediated cancer.