Process for preparing 2,2-difluoroethylamine derivatives by alkylating 2,2-difluoroethylamine
    5.
    发明授权
    Process for preparing 2,2-difluoroethylamine derivatives by alkylating 2,2-difluoroethylamine 有权
    通过烷基化2,2-二氟乙胺制备2,2-二氟乙胺衍生物的方法

    公开(公告)号:US09376389B2

    公开(公告)日:2016-06-28

    申请号:US14411173

    申请日:2013-06-24

    IPC分类号: C07D213/61

    CPC分类号: C07D213/61

    摘要: A method for preparing a 2,2-difluoroethylamine of the formula (III) in which 2,2-difluoroethylamine of the formula (I) is reacted with a halide of the formula (II) in the presence of a tertiary nitrogen base: where, in the formulae (II) and (III), Hal and A are defined as stated in the description.

    摘要翻译: 一种制备式(III)的2,2-二氟乙胺的方法,其中式(I)的2,2-二氟乙胺与式(II)的卤化物在叔氮碱的存在下反应:其中 在式(II)和(III)中,Hal和A如说明书所述定义。