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公开(公告)号:US20230304957A1
公开(公告)日:2023-09-28
申请号:US18187453
申请日:2023-03-21
Inventor: Alfonso BERDUQUE , David Bolognia , William W. Hanley , Richard Doyle , Louis M. McGrath , Julie Byard , Alan J. O'Donnell
IPC: G01N27/30
CPC classification number: G01N27/301
Abstract: A reference electrode of an electrochemical sensor includes a substrate having a well, a channel, and a conductive element. The well extends from a first surface of a substrate towards a second surface of the substrate. The channel is within the substrate. A longitudinal axis of the channel may be substantially perpendicular to a longitudinal axis of the well. The channel has a first end connected to the well and a second end that is in contact with the conductive element. The channel and the wells form a flow path of a conductive medium. The flow path may be coupled to a manipulating element such as an agitating element or heating element that promotes flow of the membrane.
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公开(公告)号:US20230304956A1
公开(公告)日:2023-09-28
申请号:US18187441
申请日:2023-03-21
Inventor: Alfonso Berduque , David Bolognia , William W. Hanley , Richard Doyle , Louise M. MaGrath , Julie Byard , Alan J. O'Donnell
IPC: G01N27/30 , G01N27/327
CPC classification number: G01N27/301 , G01N27/3272
Abstract: A reference electrode of an electrochemical sensor includes a substrate having well, a channel, and a conductive element therein. The well extends from a first surface of a substrate towards a second surface of the substrate. The channel is within the substrate. A longitudinal axis of the channel may be substantially perpendicular to a longitudinal axis of the well. The channel has a first end connected to the well and the conductive element is exposed to a second of the channel. The channel and the wells form a flow path of a conductive medium. A valve is coupled to the flow path and configured to control a flow of the conductive medium to the electrically conductive element through the flow path.
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公开(公告)号:US20250012759A1
公开(公告)日:2025-01-09
申请号:US18762515
申请日:2024-07-02
Inventor: Alfonso Berduque , Alan O'Donnell , Simone Mullins , Joyce Wu , Junfei Xia , Richard Doyle
IPC: G01N27/416
Abstract: The present disclosure provides methods and systems for reducing interference by one or more bubbles in a sensing assembly. Bubble prevention arrangements can use surfaces located in a fluid channel to provide surfaces with higher affinity for bubbles relative to the other surfaces so that the surface retains one or more bubbles within a bubble collection region; and/or to divert at least a portion of any bubbles passing through an opening in the fluid channel. Additionally or alternatively, bubble prevention arrangements comprise an agitation device configured to agitate liquid within the fluid channel. Additionally or alternatively, bubble prevention arrangements are configured to displace one or more bubbles in a region on or adjacent the sensing surface so as to reduce interference of one or more bubbles on the sensing surface.
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公开(公告)号:US20240418667A1
公开(公告)日:2024-12-19
申请号:US18746929
申请日:2024-06-18
Inventor: Alfonso Berduque , Nakkiran Arulmozhi , Louise McGrath , Richard Doyle
IPC: G01N27/30 , G01N27/416
Abstract: Systems and methods for reference electrodes are disclosed. In one aspect, a measurement system includes a pseudo-reference electrode configured to provide a reference potential and a dependence electrode configured to generate a dependence potential when exposed to a sample. Both the reference potential and the dependence potential vary based on a property of the sample. An electrochemical sensor includes the pseudo-reference electrode and the dependence electrode.
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公开(公告)号:US20250012758A1
公开(公告)日:2025-01-09
申请号:US18348877
申请日:2023-07-07
Inventor: Alfonso BERDUQUE , Alan Odonnell , Simone Mullins , Joyce Wu , Junfei Xia , Richard Doyle , Donal MCAULIFFE
IPC: G01N27/416 , G01N27/02
Abstract: The present disclosure provides methods and systems for reducing interference by one or more bubbles in a sensing assembly by determining a first property of the solution and using the first property in a removal step.
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