公开(公告)号：US20150335748A1

公开(公告)日：2015-11-26

申请号：US14613501

申请日：2015-02-04

Applicant: Amgen Inc.

Inventor： Tiangsheng LI ,  Christopher James Sloey

IPC: A61K47/10 ,  A61K39/395

Abstract: A method of stabilizing an aqueous protein or antibody formulation is disclosed herein. Additionally, stable pharmaceutical formulations are contemplated which comprise a biologically active protein, a destabilizing concentration of preservative and a stabilizing concentration of osmolyte.

Abstract translation: 本文公开了稳定水性蛋白质或抗体制剂的方法。 此外，涵盖稳定的药物制剂，其包含生物活性蛋白质，去稳定浓度的防腐剂和稳定的渗透液浓度。