公开(公告)号：US11033684B2

公开(公告)日：2021-06-15

申请号：US15762939

申请日：2016-10-28

Applicant: AMGEN INC.

Inventor： Hans Stenberg Knudsen ,  Christian Plambech ,  Rasmus Øhlenschlæger ,  Jørgen Jørgensen

IPC: A61M5/20 ,  A61M5/145 ,  A61M5/32 ,  A61M5/142 ,  A61M5/315

Abstract: A single-use auto-injector includes a housing and a dosing unit in at least part of the housing. The dosing unit includes a needle, a drug container with drug, a piston movable in the container, a first mechanical power supply for moving the piston to deliver the drug, an activation mechanism, and a mechanical escapement mechanism for controlling the movement of the piston. The auto-injector has a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate a human body, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks. A second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state.

公开(公告)号：US20250082858A1

公开(公告)日：2025-03-13

申请号：US18962542

申请日：2024-11-27

Applicant: AMGEN INC.

Inventor： Hans Stenberg Knudsen ,  Christian Plambech ,  Rasmus Øhlenschlæger ,  Jørgen Jørgensen

IPC: A61M5/20 ,  A61M5/142 ,  A61M5/145 ,  A61M5/315 ,  A61M5/32

Abstract: A single-use auto-injector includes a housing and a dosing unit in at least part of the housing. The dosing unit includes a needle, a drug container with drug, a piston movable in the container, a first mechanical power supply for moving the piston to deliver the drug, an activation mechanism, and a mechanical escapement mechanism for controlling the movement of the piston. The auto-injector has a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate a human body, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks. A second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state.

公开(公告)号：US12186536B2

公开(公告)日：2025-01-07

申请号：US17323830

申请日：2021-05-18

Applicant: AMGEN INC.

Inventor： Hans Stenberg Knudsen ,  Christian Plambech ,  Rasmus Øhlenschlæger ,  Jørgen Jørgensen

IPC: A61M5/20 ,  A61M5/145 ,  A61M5/32 ,  A61M5/142 ,  A61M5/315

Abstract: A single-use auto-injector includes a housing and a dosing unit in at least part of the housing. The dosing unit includes a needle, a drug container with drug, a piston movable in the container, a first mechanical power supply for moving the piston to deliver the drug, an activation mechanism, and a mechanical escapement mechanism for controlling the movement of the piston. The auto-injector has a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate a human body, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks. A second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state.

公开(公告)号：US20210268192A1

公开(公告)日：2021-09-02

申请号：US17323830

申请日：2021-05-18

Applicant: AMGEN INC.

Inventor： Hans Stenberg Knudsen ,  Christian Plambech ,  Rasmus Øhlenschlæger ,  Jørgen Jørgensen

IPC: A61M5/20 ,  A61M5/145 ,  A61M5/32

Abstract: A single-use auto-injector includes a housing and a dosing unit in at least part of the housing. The dosing unit includes a needle, a drug container with drug, a piston movable in the container, a first mechanical power supply for moving the piston to deliver the drug, an activation mechanism, and a mechanical escapement mechanism for controlling the movement of the piston. The auto-injector has a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate a human body, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks. A second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state.

公开(公告)号：US20180304014A1

公开(公告)日：2018-10-25

申请号：US15762939

申请日：2016-10-28

Applicant: AMGEN INC.

Inventor： Hans Stenberg Knudsen ,  Christian Plambech ,  Rasmus Øhlenschlæger ,  Jørgen Jørgensen

IPC: A61M5/20 ,  A61M5/145 ,  A61M5/32

CPC classification number: A61M5/2033 ,  A61M5/1454 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/14256 ,  A61M2005/14506 ,  A61M2005/206 ,  A61M2005/31518 ,  A61M2005/3267

Abstract: A single-use auto-injector includes a housing and a dosing unit in at least part of the housing. The dosing unit includes a needle, a drug container with drug, a piston movable in the container, a first mechanical power supply for moving the piston to deliver the drug, an activation mechanism, and a mechanical escapement mechanism for controlling the movement of the piston. The auto-injector has a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate a human body, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks. A second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state.