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1.发明申请SYNTHETIC PROCESS FOR ANTICANCER DRUG FLUORAPACIN AND TRISULFIDE DERIVATEVES 有权抗生素药物氟洛地平和三聚体衍生物的合成方法公开(公告)号：US20100191016A1
公开(公告)日：2010-07-29
申请号：US12413385
申请日：2009-03-27
Applicant: Haoyun An , Xiaopeng Mo
Inventor： Haoyun An , Xiaopeng Mo
IPC: C07C321/20
CPC classification number: C07C319/24 , C07C319/28 , C07C323/07
Abstract: The invention provides a synthetic and manufacturing process for the preparation of the anticancer drug, fluorapacin, bis(4-fluorobenzyl)trisulfide, and related trisulfide derivatives on large scale. Also provided are processes for the purification and isolation of fluorapacin having high purity and improved stability.
Abstract translation: 本发明提供了大规模制备抗癌药物，氟卡宾，双（4-氟苄基）三硫化物和相关三硫化物衍生物的合成和制备方法。 还提供了用于纯化和分离具有高纯度和改善的稳定性的氟沙平的方法。
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2.发明授权Synthetic process for anticancer drug fluorapacin and trisulfide derivatives 有权抗癌药物氟沙星和三硫化物衍生物的合成方法公开(公告)号：US07851657B2
公开(公告)日：2010-12-14
申请号：US12413385
申请日：2009-03-27
Applicant: Haoyun An , Xiaopeng Mo
Inventor： Haoyun An , Xiaopeng Mo
IPC: C07C321/00
CPC classification number: C07C319/24 , C07C319/28 , C07C323/07
Abstract: The invention provides a synthetic and manufacturing process for the preparation of the anticancer drug, fluorapacin, bis(4-fluorobenzyl)trisulfide, and related trisulfide derivatives on large scale. Also provided are processes for the purification and isolation of fluorapacin having high purity and improved stability.
Abstract translation: 本发明提供了大规模制备抗癌药物，氟卡宾，双（4-氟苄基）三硫化物和相关三硫化物衍生物的合成和制备方法。 还提供了用于纯化和分离具有高纯度和改善的稳定性的氟沙平的方法。
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