- 专利标题: Synthesis of imidazo[1,2-a]pyrazin-4-ium salts for the synthesis of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof
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申请号: US14079530申请日: 2013-11-13
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公开(公告)号: US09981967B2公开(公告)日: 2018-05-29
- 发明人: Franck Denat , Pauline Desogere , Claire Bernhard , Yoann Rousselin , Frederic Boschetti
- 申请人: UNIVERSITE DE BOURGOGNE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- 申请人地址: FR Dijon FR Paris
- 专利权人: UNIVERSITE DE BOURGOGNE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- 当前专利权人: UNIVERSITE DE BOURGOGNE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- 当前专利权人地址: FR Dijon FR Paris
- 代理机构: Young & Thompson
- 优先权: FR1261091 20121121
- 主分类号: C07D255/02
- IPC分类号: C07D255/02 ; C07D487/04 ; C07D401/14 ; C07F9/6515 ; C07D401/06 ; C07D301/02 ; A61K49/00 ; A61K49/10 ; A61K51/04 ; B01J31/18
摘要:
The present invention embodiments relate to a compound with formula (V′) The invention also relates in certain embodiments to the synthesis method for compound (V′) and its use for the preparation of 1,4,7-triazacyclononane (tacn) and N- and/or C-functionalized derivatives thereof, particularly compounds with formula (I) The invention also relates in certain embodiments to metallic complexes comprising a ligand with formula (I) and a metal and their use for imaging.
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