- 专利标题: Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors
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申请号: US15186697申请日: 2016-06-20
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公开(公告)号: US09918990B2公开(公告)日: 2018-03-20
- 发明人: Eddy W. Yue , Andrew P. Combs , Brent Douty
- 申请人: Incyte Corporation
- 申请人地址: US DE Wilmington
- 专利权人: Incyte Corporation
- 当前专利权人: Incyte Corporation
- 当前专利权人地址: US DE Wilmington
- 代理机构: Fish & Richardson P.C.
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/538 ; A61K31/437 ; A61K31/4545 ; A61K31/496 ; A61K31/498 ; A61K31/519 ; A61K31/5377
摘要:
The present invention relates to compounds represented by the general Formula I which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer.
公开/授权文献
- US20170014418A1 BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS 公开/授权日:2017-01-19
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