Invention Grant
- Patent Title: Single domain antibodies capable of modulating BACE activity
-
Application No.: US14023586Application Date: 2013-09-11
-
Publication No.: US09908943B2Publication Date: 2018-03-06
- Inventor: Bart De Strooper , Els Marjaux , Lujia Zhou , Serge Muyldermans
- Applicant: VIB VZW , KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R&D , VRIJE UNIVERSITEIT BRUSSEL
- Applicant Address: BE Ghent BE Leuven BE Brussels
- Assignee: VIB VZW,KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D,VRIJE UNIVERSITEIT BRUSSEL
- Current Assignee: VIB VZW,KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D,VRIJE UNIVERSITEIT BRUSSEL
- Current Assignee Address: BE Ghent BE Leuven BE Brussels
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C07K16/40
- IPC: C07K16/40
Abstract:
Described are single domain antibodies with a specificity for BACE1. More specifically, described are single variable-domain antibodies derived from camelids that bind to BACE1 and are capable of inhibiting the activity of BACE1. The antibodies can be used for research and medical applications. Specific applications include the use of BACE1-specific antibodies for the treatment of Alzheimer's disease.
Public/Granted literature
- US20160237166A9 SINGLE DOMAIN ANTIBODIES CAPABLE OF MODULATING BACE ACTIVITY Public/Granted day:2016-08-18
Information query
