Invention Grant
- Patent Title: Bessel beam plane illumination microscope
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Application No.: US14215976Application Date: 2014-03-17
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Publication No.: US09891421B2Publication Date: 2018-02-13
- Inventor: Robert E. Betzig
- Applicant: Howard Hughes Medical Institute
- Applicant Address: US VA Ashburn
- Assignee: Howard Hughes Medical Institute
- Current Assignee: Howard Hughes Medical Institute
- Current Assignee Address: US VA Ashburn
- Agency: Brake Hughes Bellermann LLP
- Main IPC: H04N9/47
- IPC: H04N9/47 ; G03H1/00 ; G02F1/01 ; G02B21/06 ; G02B21/36 ; G02B21/00 ; G02B27/09

Abstract:
A microscope has a light source for generating a light beam having a wavelength, λ, and beam-forming optics configured for receiving the light beam and generating a Bessel-like beam that is directed into a sample. The beam-forming optics include an excitation objective having an axis oriented in a first direction. Imaging optics are configured for receiving light from a position within the sample that is illuminated by the Bessel-like beam and for imaging the received light on a detector. The imaging optics include a detection objective having an axis oriented in a second direction that is non-parallel to the first direction. A detector is configured for detecting signal light received by the imaging optics, and an aperture mask is positioned.
Public/Granted literature
- US20140198200A1 BESSEL BEAM PLANE ILLUMINATION MICROSCOPE Public/Granted day:2014-07-17
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