Invention Grant
- Patent Title: 2-aminothiazole derivative or salt thereof
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Application No.: US15506561Application Date: 2015-08-25
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Publication No.: US09844549B2Publication Date: 2017-12-19
- Inventor: Taisuke Takahashi , Hiroaki Tanaka , Michinori Akaiwa , Kenji Negoro , Hisashi Mihara , Hideyoshi Fuji , Hajime Takamatsu
- Applicant: ASTELLAS PHARMA INC.
- Applicant Address: JP Chuo-ku
- Assignee: Astellas Pharma Inc.
- Current Assignee: Astellas Pharma Inc.
- Current Assignee Address: JP Chuo-ku
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2014-171092 20140826
- International Application: PCT/JP2015/073914 WO 20150825
- International Announcement: WO2016/031833 WO 20160303
- Main IPC: C07D417/14
- IPC: C07D417/14 ; A61K31/506 ; A61K31/496 ; A61K31/4439 ; C07D417/12

Abstract:
A compound which is useful as an active ingredient for a pharmaceutical composition for treating urine storage dysfunction, voiding dysfunction, lower urinary tract dysfunction, and the like. The present inventors have found that a 2-aminothiazole derivative has an excellent muscarinic M3 receptor-positive allosteric modulator activity and is expected as an agent for preventing or treating bladder/urinary tract diseases associated with bladder contractions via a muscarinic M3 receptor, thereby completing the present invention. 2-aminothiazole derivative or a salt thereof of the present invention is expected as an agent for preventing or treating bladder/urinary tract diseases associated with bladder contractions via a muscarinic M3 receptor, for example voiding dysfunction such as underactive bladder.
Public/Granted literature
- US20170290824A1 2-AMINOTHIAZOLE DERIVATIVE OR SALT THEREOF Public/Granted day:2017-10-12
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