- 专利标题： Chimeric antigen receptor and methods of use thereof
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申请号： US15419729申请日： 2017-01-30
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公开(公告)号： US09821012B2公开(公告)日： 2017-11-21
- 发明人: Chia-Yung Wu , James Onuffer , Wendell A. Lim
- 申请人： The Regents of the University of California
- 申请人地址： US CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： US CA Oakland
- 代理机构： Bozicevic Field & Francis, LLP
- 代理商 Paula A. Borden; Otto C. Guedelhoefer
- 主分类号： C12N5/071
- IPC分类号： C12N5/071 ; C12N5/16 ; A61K35/17 ; C07K14/705 ; C07K16/18 ; C07K16/28 ; C07K14/725 ; C12N9/90 ; C12N9/14 ; C12N5/0783 ; A61K47/68 ; A61K39/00
摘要：
The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided.
公开/授权文献
- US20170143765A1 CHIMERIC ANTIGEN RECEPTOR AND METHODS OF USE THEREOF 公开/授权日：2017-05-25
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