A separation alert device for warning a user of separation from an item includes a housing that defines an internal space. The housing is configured for retention on the user's person. A power module, a microprocessor, a first proximity sensor and a plurality of alarms are coupled to the housing and are positioned in the internal space. The microprocessor is operationally coupled to the power module. The first proximity sensor and the alarms are operationally coupled to the microprocessor. A second proximity sensor is in wireless communication with the microprocessor. The second proximity sensor is coupled to an item that the user desires to retain proximate to the user. The microprocessor is positioned to receive a location signal from the second proximity sensor. Separation of the first proximity sensor by a preset distance from the second proximity sensor will compel the microprocessor to compel the alarms to notify the user.