- 专利标题： Bile acid derivatives as FXR ligands for the prevention or treatment of FXR-mediated diseases or conditions
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申请号： US14743295申请日： 2015-06-18
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公开(公告)号： US09763964B2公开(公告)日： 2017-09-19
- 发明人: Roberto Pellicciari , Stefano Fiorucci , Mark Pruzanski
- 申请人： Intercept Pharmaceuticals, Inc.
- 申请人地址： US NY New York
- 专利权人： Intercept Pharmaceuticals, Inc.
- 当前专利权人： Intercept Pharmaceuticals, Inc.
- 当前专利权人地址： US NY New York
- 代理机构： Intercept Pharmaceuticals, Inc.
- 代理商 Michelle Iwamoto-Fan
- 主分类号： A61K31/575
- IPC分类号： A61K31/575 ; C07J9/00 ; C07J31/00
摘要：
The present invention relates to compounds of formula (I): wherein R is hydrogen or alpha-hydroxy, the hydroxyl group in position 7 is in the alpha or beta position; and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof.
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