Invention Grant
- Patent Title: Calcium propane-2-sulfinate dihydrate
-
Application No.: US15175821Application Date: 2016-06-07
-
Publication No.: US09757367B2Publication Date: 2017-09-12
- Inventor: Sebastien Caille , Filisaty Vounatsos
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Markus Bergauer
- Main IPC: C07C313/02
- IPC: C07C313/02 ; A61K31/451 ; C07D211/94 ; C07D491/048 ; C07C309/25 ; C07C309/04 ; C07D498/04 ; C07D211/76 ; C07C309/35
Abstract:
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid as well as intermediates and processes for making the intermediates. Also provided are crystalline forms of the compound and the intermediates.
Public/Granted literature
- US20160289178A1 PROCESSES OF MAKING AND CRYSTALLINE FORMS OF A MDM2 INHIBITOR Public/Granted day:2016-10-06
Information query
