发明授权
- 专利标题: Tritoqualine hydrochloride in crystalline form and a process for obtaining same
-
申请号: US15104006申请日: 2014-12-29
-
公开(公告)号: US09718833B2公开(公告)日: 2017-08-01
- 发明人: Patrice Binay
- 申请人: Patrice Binay
- 代理机构: Oliff PLC
- 优先权: FR1303107 20131230
- 国际申请: PCT/FR2014/000306 WO 20141229
- 国际公布: WO2015/101727 WO 20150709
- 主分类号: C07D491/056
- IPC分类号: C07D491/056
摘要:
A crystalline form of tritoqualine hydrochloride and also a process for obtaining same. The process for obtaining tritoqualine hydrochloride is made of dissolving tritoqualine base in an alcohol, in particular a lower aliphatic alcohol, such as ethanol, in the presence of hydrochloric acid until a solution in the supersaturated state is obtained. Through successive additions of ether, in particular of ethyl ether, the tritoqualine hydrochloride will subsequently be able to crystallize. The product can be applied to the preparation of pharmaceutical formulations.
公开/授权文献
信息查询