发明授权
- 专利标题： Pteridine ketone derivative and applications thereof as EGFR, BLK, and FLT3 inhibitor
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申请号： US14400508申请日： 2013-04-02
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公开(公告)号： US09670213B2公开(公告)日： 2017-06-06
- 发明人: Honglin Li , Yufang Xu , Zhenjiang Zhao , Xiaofeng Liu , Wei Zhou , Fang Bai , Mengzhu Xue , Lei Zhang , Youli Zhang
- 申请人： EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
- 申请人地址： CN Shanghai
- 专利权人： East China University of Science and Technology
- 当前专利权人： East China University of Science and Technology
- 当前专利权人地址： CN Shanghai
- 代理机构： Weaver Austin Villeneuve & Sampson LLP
- 代理商 Tom Hunter
- 优先权： CN201210148939 20120514; CN201210484897 20121123
- 国际申请： PCT/CN2013/073612 WO 20130402
- 国际公布： WO2013/170671 WO 20131121
- 主分类号： C07D401/12
- IPC分类号： C07D401/12 ; C07D475/04 ; C07D487/02 ; C07D475/00 ; C07D239/50
摘要：
Provided are a pteridine ketone derivative used as an EGFR, BLK, and FLT3 inhibitor and applications thereof. Specifically, provided are a compound of the following formula I, a pharmaceutical composition containing the compound of the formula I, and use of compound in preparing medicine for treating diseases mediated by EGFR, BLK, or FLT3 or inhibiting EGFR, BLK, and FLT3.
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