There is provided a signal processing device s including a noise cancellation process clock generation unit configured to generate a noise cancellation process clock having a predetermined fixed frequency, a noise canceling unit configured to include a noise canceling filter operating based on the noise cancellation process clock and generating a noise canceling signal having a signal property of canceling an external noise component based on an input audio signal including the external noise component picked up by a microphone, and an addition unit superimposing the noise canceling signal generated by the filter on a digital audio signal, and a sampling rate conversion unit configured to rate-convert the input digital audio signal sampled at a clock in asynchrony with the noise cancellation process clock to a signal at a sampling frequency in synchrony with the noise cancellation process clock and to supply the rate-converted signal to the addition unit.