发明授权
US09527813B2 Process for the synthesis of (+) and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane
有权
合成(+)和( - ) - 1-(3,4-二氯苯基)-3-氮杂双环[3.1.0]己烷的方法
- 专利标题: Process for the synthesis of (+) and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane
- 专利标题(中): 合成(+)和( - ) - 1-(3,4-二氯苯基)-3-氮杂双环[3.1.0]己烷的方法
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申请号: US13945605申请日: 2013-07-18
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公开(公告)号: US09527813B2公开(公告)日: 2016-12-27
- 发明人: Jerry A. Murry , Edward G. Corley , Feng Xu , Bryon Simmons
- 申请人: Euthymics Bioscience, Inc.
- 申请人地址: US MA Cambridge
- 专利权人: EUTHYMICS BIOSCIENCE, INC.
- 当前专利权人: EUTHYMICS BIOSCIENCE, INC.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Hoxie & Associates LLC
- 主分类号: C07D209/52
- IPC分类号: C07D209/52 ; C07C211/29 ; C07C215/38 ; C07C255/46
摘要:
The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence.
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