发明授权
- 专利标题: Indazole compounds as aldosterone synthase inhibitors
- 专利标题(中): 吲唑化合物作为醛固酮合酶抑制剂
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申请号: US14651491申请日: 2013-12-17
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公开(公告)号: US09522141B2公开(公告)日: 2016-12-20
- 发明人: Scott B. Hoyt , Jerry Andrew Taylor , Clare London , Yusheng Xiong , Andrew John Cooke
- 申请人: Merck Sharp & Dohme Corp.
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 代理商 Janet E. Fair; Anna L. Cocuzzo
- 国际申请: PCT/US2013/075528 WO 20131217
- 国际公布: WO2014/099833 WO 20140626
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; A61K31/4725 ; A61K31/497 ; C07D401/04 ; C07D403/14 ; C07D403/04
摘要:
This invention relates to indazole compounds of the structural formula: (structure represented) or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment or amelioration of conditions that could be treated by inhibiting aldosterone synthase.
公开/授权文献
- US20150320733A1 INDAZOLE COMPOUNDS AS ALDOSTERONE SYNTHASE INHIBITORS 公开/授权日:2015-11-12
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