发明授权
- 专利标题: Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
- 专利标题(中): 免疫原性表位,肽模拟物和抗肽抗体及其使用方法
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申请号: US13662024申请日: 2012-10-26
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公开(公告)号: US09504738B2公开(公告)日: 2016-11-29
- 发明人: Kaumaya Pravin
- 申请人: Ohio State Innovation Foundation
- 申请人地址: US OH Columbus
- 专利权人: Ohio State Innovation Foundation
- 当前专利权人: Ohio State Innovation Foundation
- 当前专利权人地址: US OH Columbus
- 代理机构: Meunier Carlin & Curfman LLC
- 主分类号: A61K38/16
- IPC分类号: A61K38/16 ; A61K39/00 ; C07K14/52 ; C07K14/71 ; C07K16/22 ; C07K16/32 ; A61K38/00
摘要:
Provided herein are compositions and methods for the treatment of cancers. The compositions comprise at least one VEGF peptide mimic, HER-2 epitope, immunogenic VEGF peptides, and HER-2 immunogenic epitopes. The peptides and epitopes may be linear, cyclized, retro-inverso, or a combination of such forms. Also provided herein are antibodies raised to VEGF peptide mimics, HER-2 epitopes, immunogenic VEGF peptides, and HER-2 immunogenic epitopes.
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