Invention Grant
US09487490B2 3-cyclohexenyl and cyclohexyl substituted indole and indazole compounds as RORgammaT inhibitors and uses thereof
有权
3-环己烯基和环己基取代的吲哚和吲唑化合物作为RORGAMAMT抑制剂及其用途
- Patent Title: 3-cyclohexenyl and cyclohexyl substituted indole and indazole compounds as RORgammaT inhibitors and uses thereof
- Patent Title (中): 3-环己烯基和环己基取代的吲哚和吲唑化合物作为RORGAMAMT抑制剂及其用途
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Application No.: US14421057Application Date: 2013-08-14
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Publication No.: US09487490B2Publication Date: 2016-11-08
- Inventor: Kenneth J. Barr , John K. Maclean , Hongjun Zhang , Richard T. Beresis , Dongshan Zhang , Brian M. Andresen , Neville J. Anthony , Blair T. Lapointe , Nunzio Sciammetta
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agency: Goodwin Procter LLP
- Priority: CNPCT/CN2012/080133 20120815
- International Application: PCT/US2013/054902 WO 20130814
- International Announcement: WO2014/028597 WO 20140220
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/4745 ; C07D231/56 ; A61K31/404 ; A61K31/416 ; A61K31/437 ; A61K31/454 ; A61K31/496 ; A61K31/5377 ; C07D209/26 ; C07D401/06 ; C07D403/06 ; C07D405/12 ; C07D413/06
Abstract:
The present invention relates to compounds according to Formula I and pharmaceutically acceptable salts or solvates thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or conditions.
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