Invention Grant
- Patent Title: Disintegrating particle composition and orally rapidly disintegrating tablet
- Patent Title (中): 崩解颗粒组合物和口服快速崩解片剂
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Application No.: US13389880Application Date: 2010-08-11
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Publication No.: US09446055B2Publication Date: 2016-09-20
- Inventor: Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
- Applicant: Keiichi Fujiwara , Tadashi Fukami , Haruka Koizumi
- Applicant Address: JP Toyama
- Assignee: FUJI CHEMICAL INDUSTRY CO., LTD.
- Current Assignee: FUJI CHEMICAL INDUSTRY CO., LTD.
- Current Assignee Address: JP Toyama
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2009-186646 20090811
- International Application: PCT/JP2010/063601 WO 20100811
- International Announcement: WO2011/019045 WO 20110217
- Main IPC: A61K47/26
- IPC: A61K47/26 ; A61K31/167 ; A61K9/14 ; A61K31/616 ; A61K9/00 ; A61K9/20

Abstract:
There has been a need for an orally rapidly disintegrating tablet which has a good texture and taste in the oral cavity, such a sufficient hardness as not giving any worry of being chipped or dusted during production or transportation and good disintegrating properties in the oral cavity and can sustain a sufficient hardness even under humid conditions after opening. Disclosed are a disintegrating particle composition which is prepared by dispersing, in the presence of water, mannitol, xylitol, an inorganic excipient, a disintegrating agent and carmellose and drying, and an orally rapidly disintegrating tablet which comprises said disintegrating particle composition, an active substance and a disintegrating agent. The disintegrating tablet has a good texture and taste, an appropriate hardness and good disintegrating properties and can sustain a sufficient hardness under humid conditions.
Public/Granted literature
- US20120156261A1 DISINTEGRATING PARTICLE COMPOSITION AND ORALLY RAPIDLY DISINTEGRATING TABLET Public/Granted day:2012-06-21
Information query
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