- 专利标题: Swallowable capsule and method for stimulating incretin production within the intestinal tract
-
申请号: US14599350申请日: 2015-01-16
-
公开(公告)号: US09403002B2公开(公告)日: 2016-08-02
- 发明人: Mir A. Imran , Mir Hashim , Emily Arnsdorf
- 申请人: InCube Labs, LLC
- 申请人地址: US CA San Jose
- 专利权人: Rani Therapeutics, LLC
- 当前专利权人: Rani Therapeutics, LLC
- 当前专利权人地址: US CA San Jose
- 代理机构: Wilson Sonsini Goodrich & Rosati
- 主分类号: A61N1/36
- IPC分类号: A61N1/36 ; A61K38/26 ; A61N1/05 ; A61N1/372 ; A61N1/06
摘要:
Embodiments of the invention provide apparatus and methods for stimulating L cells in the intestinal tract to produce incretins for the treatment of conditions including diabetes and obesity. Many embodiments provide a method and apparatus for the treatment of diabetes by electrically stimulating L-cells to secrete incretins to stimulate or otherwise modulate the production of insulin. Particular embodiments provide a swallowable capsule for stimulating L-cells in the intestinal tract as the capsule moves through the tract. The capsule can include two or more electrodes for providing electrical stimulation to L-cells, a power source for powering one or more components of the capsule, a sensor for sensing the location of the capsule in the intestinal tract; a controller and a waveform generator for generating the electrical signals emitted by the electrodes to stimulate the L-cells to secrete incretins such as GLP-1 to stimulate insulin production for glucose regulation of diabetic conditions.
公开/授权文献
信息查询