发明授权
US09394315B2 Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease
有权
四氢[1,8]萘啶磺酰胺和相关化合物，用作RORγ的激动剂和治疗疾病
![Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease](/docs/US/2016-07-19/US09394315B2/abs.jpg.600x600.jpg)
- 专利标题： Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease
- 专利标题（中）： 四氢[1,8]萘啶磺酰胺和相关化合物，用作RORγ的激动剂和治疗疾病
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申请号： US14398774申请日： 2013-05-08
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公开(公告)号： US09394315B2公开(公告)日： 2016-07-19
- 发明人: Thomas D. Aicher , Peter L. Toogood , Xiao Hu
- 申请人： Lycera Corporation
- 申请人地址： US MI Ann Arbor
- 专利权人： Lycera Corporation
- 当前专利权人： Lycera Corporation
- 当前专利权人地址： US MI Ann Arbor
- 代理机构： Goodwin Procter LLP
- 国际申请： PCT/US2013/040085 WO 20130508
- 国际公布： WO2013/169864 WO 20131114
- 主分类号： C07D498/04
- IPC分类号： C07D498/04 ; C07D471/04 ; C07D491/052
![Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease](/abs-image/US/2016/07/19/US09394315B2/abs.jpg.150x150.jpg)
摘要：
The invention provides tetrahydro[1,8]naphthyridine and related compounds, pharmaceutical compositions, methods of promoting RORγ activity, increasing the amount of IL-17 in a subject, and treating cancer, bacterial infections, and fungal infections using such tetrahydro[1,8]naphthyridine and related compounds.
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