A method selects mobile station candidates for use with virtual multiple-input multiple-output (“V-MIMO”) in a communication system. The communication system includes at least one base station and a plurality of mobile stations. At least one downlink metric is determined for a first mobile station. The at least one downlink metric is used to determine eligibility for uplink V-MIMO candidate list selection. Responsive to determining that the first mobile station is eligible for uplink V-MIMO candidate list selection, the first mobile station is paired with a second mobile station eligible for uplink V-MIMO candidate list selection.