发明授权
- 专利标题： Differentiation of human embryonic stem cells into single hormonal insulin positive cells
- 专利标题（中）： 将人胚胎干细胞分化为单一激素胰岛素阳性细胞
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申请号： US13708369申请日： 2012-12-07
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公开(公告)号： US09388386B2公开(公告)日： 2016-07-12
- 发明人: Alireza Rezania
- 申请人： Janssen Biotech, Inc.
- 申请人地址： US PA Horsham
- 专利权人： Janssen Biotech, Inc.
- 当前专利权人： Janssen Biotech, Inc.
- 当前专利权人地址： US PA Horsham
- 代理商 Lois A. Gianneschi
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/02 ; C12N5/071
摘要：
The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides methods to produce a population of cells, wherein greater than 10% of the cells in the population express markers characteristic of single hormonal pancreatic beta cells.
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