发明授权
US09388382B2 Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells
有权
分离CD14阴性，CD45阳性和CD117阳性胚胎样干细胞免于人脐带血单核细胞单核细胞
- 专利标题： Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells
- 专利标题（中）： 分离CD14阴性，CD45阳性和CD117阳性胚胎样干细胞免于人脐带血单核细胞单核细胞
-
申请号： US12099054申请日： 2008-04-07
-
公开(公告)号： US09388382B2公开(公告)日： 2016-07-12
- 发明人: Yong Zhao , Theodore Mazzone
- 申请人： Yong Zhao , Theodore Mazzone
- 申请人地址： US IL Urbana
- 专利权人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- 当前专利权人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- 当前专利权人地址： US IL Urbana
- 代理机构： Greenberg Traurig, LLP
- 代理商 Weisun Rao
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/074 ; A61K35/12
摘要：
The present invention is related generally to embryonic-like stem cells isolated from human umbilical cord blood, designated herein as cord blood-stem cells (CB-SC's), which display the characteristics of embryonic stem cells and hematopoietic cells. These cells have the capability of proliferation and are able to differentiate to multiple types of cells. In addition, the CB-SC display low immunogenicity and immune regulation. These cells are, therefore, suitable for use in stem cell-based therapies for the treatment of diseases such as Parkinson's disease, diabetes, spinal cord damage, multiple sclerosis, cardiovascular disease, stroke and birth defects, and for preventing, treating and/or reducing an autoimmune disease in a mammalian subject.
公开/授权文献
信息查询
