发明授权
- 专利标题: Ring-fused compound
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申请号: US14619980申请日: 2015-02-11
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公开(公告)号: US09359350B2公开(公告)日: 2016-06-07
- 发明人: Keita Nagai , Koh Nagasawa , Hirobumi Takahashi , Motoaki Baba , Shinichi Fujioka , Eri Kondoh , Kenichi Tanaka , Yoshiki Itoh
- 申请人: SATO PHARMACEUTICAL CO., LTD.
- 申请人地址: JP Tokyo
- 专利权人: SATO PHARMACEUTICAL CO., LTD.
- 当前专利权人: SATO PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: JP Tokyo
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2011-016950 20110128
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; A61K31/437 ; C07D471/04 ; C07D209/08 ; C07D209/30 ; C07D231/56 ; C07D235/08 ; C07D235/10 ; C07D401/06 ; C07D405/06 ; C07D235/06 ; C07D403/04 ; C07D409/06 ; C07D413/06 ; C07D209/12
摘要:
The present invention relates to a compound that has URAT1 inhibitory action, and a URAT1 inhibitor, a blood uric acid level-reducing agent and a pharmaceutical composition comprising the compound. More specifically, the present invention relates to a compound represented by Formula (I) below. [in the formula, R1 is -Q1-A1 and the like; is a double bond or a single bond; when is a double bond, W1 is a nitrogen atom or a group represented by the general formula: ═C(Ra)—, and W2 is a nitrogen atom or a group represented by the general formula: ═C(Rb)—; when is a single bond, W1 is a group represented by the general formula: —C(Raa)(Rab)— or a group represented by the general formula: —(C═O)—, and W2 is a group represented by the general formula: —C(Rba)(Rbb)—, a group represented by the general formula: —(C═O)— or a group represented by the general formula: —N(Rbc)—; W3, W4 and W5 are each independently a nitrogen atom or a methine group and the like that may have a substituent; X is a single bond, an oxygen atom and the like; Y is a single bond or (CRYiRYi′)n; and Z is a hydroxyl group or COOR2 and the like.
公开/授权文献
- US20150203490A1 RING-FUSED COMPOUND 公开/授权日:2015-07-23
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