发明授权
US09339535B2 Vaccines and immunopotentiating compositions and methods for making and using them
有权
疫苗和免疫增强组合物和制备和使用它们的方法
- 专利标题: Vaccines and immunopotentiating compositions and methods for making and using them
- 专利标题(中): 疫苗和免疫增强组合物和制备和使用它们的方法
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申请号: US13324887申请日: 2011-12-13
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公开(公告)号: US09339535B2公开(公告)日: 2016-05-17
- 发明人: Denis Leclerc , Nathalie Majeau , Constantino Roberto Lopez-Macias, III , Alain Lamarre
- 申请人: Denis Leclerc , Nathalie Majeau , Constantino Roberto Lopez-Macias, III , Alain Lamarre
- 申请人地址: CA Quebec
- 专利权人: FOLIA BIOTECH, INC.
- 当前专利权人: FOLIA BIOTECH, INC.
- 当前专利权人地址: CA Quebec
- 代理机构: Greer Burns & Crain, Ltd.
- 代理商 Gregory P. Einhorn
- 主分类号: A61K39/12
- IPC分类号: A61K39/12 ; A61K39/02 ; C07K14/005 ; C07K14/62 ; C12N7/00 ; A61K39/00
摘要:
An immunopotentiating composition comprising a papaya mosaic virus (PapMV), or a virus-like particle (VLP) derived from PapMV coat protein, which is capable of functioning as an adjuvant and thus potentiating an immune response in an animal is provided. The immunopotentiating composition can further comprise an immunogen, which can be fused or otherwise linked to the VLP, or not linked to the VLP. The immunopotentiating composition is capable of potentiating a humoral and/or a cellular response in the animal and is suitable for use as an adjuvant or vaccine. Methods of potentiating an immune response in an animal comprising administering to the animal an immunopotentiating composition are also provided have application in both human and veterinary medicine.
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