A medical instrument guiding device includes a body base component, and a guide body upper component assembled to the body base component. The guide body upper component has a substantially semi-spherical shape to house a medical instrument guide ball resting on a friction surface located within the body base component. The surface of the guide body upper component includes a cut out working area, and a surface of the medical instrument guide ball is exposed by the cut out working area. A medical instrument port is arranged on a truncated surface of the medical instrument guide ball, and a medical instrument may be passed through the medical instrument port. The medical instrument guide ball permits the medical instrument to be moved in three dimensions. The medical instrument port permits the medical instrument to be advanced into a patient.