A compression integument for applying controllable intermittent sequential compression to the limbs of a user comprises an elongated fabric body sized to encircle a limb of a user, one or more compressible pads affixed to a surface of the fabric body facing the limb when the fabric body is wrapped around the limb; one or more tensioning elements integrated into the fabric body or compressible pads and arranged to encircle the limb when the fabric body is wrapped around the limb, and a micro-processor based actuator for selectively actuating the one or more tensioning elements to reduce the effective diameter of the tensioning elements encircling the limb, to thereby apply pressure to the limb by way of the compressible pads.