Handling network data packets classified as being high throughput and low latency with a network traffic management device is disclosed. Packets are received from a network and classified as high throughput or low latency based on packet characteristics or other factors. Low latency classified packets are generally processed immediately, such as upon receipt, while the low latency packet processing is strategically interrupted to enable processing coalesced high throughput classified packets in an optimized manner. The determination to cease processing low latency packets in favor of high throughput packets may be based on a number of factors, including whether a threshold number of high throughput classified packets are received or based on periodically polling a high throughput packet memory storage location.