A self-contained, hand-held device for providing a dermatological treatment may include a device body configured to be handheld by a user, a radiation source including a beam source configured to generate an energy beam, an application end configured to be manually moved across the surface of the skin, a sensor configured to generate signals based on an interaction with the skin, and electronics configured to automatically identify a series of intrinsic skin features based on the sensor signals, and control at least one operational parameter of the radiation source based at least on the identification of such skin features.