- 专利标题： Polypeptides having nucleic acid binding activity and compositions and methods for nucleic acid amplification
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申请号： US13613476申请日： 2012-09-13
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公开(公告)号： US09267130B2公开(公告)日： 2016-02-23
- 发明人: Patrick K. Martin , David A. Simpson , Christine D. Hardy
- 申请人： Patrick K. Martin , David A. Simpson , Christine D. Hardy
- 申请人地址： US CA Carlsbad
- 专利权人： APPLIED BIOSYSTEMS, LLC
- 当前专利权人： APPLIED BIOSYSTEMS, LLC
- 当前专利权人地址： US CA Carlsbad
- 主分类号： C12N9/96
- IPC分类号： C12N9/96 ; C07K14/195 ; C12N9/12 ; C12Q1/68
摘要：
Polypeptides having nucleic acid binding activity are provided. Methods of using polypeptides having nucleic acid binding activity are provided. Fusion proteins and methods of using fusion proteins are provided. Fusion proteins comprising a polymerase and a nucleic acid binding polypeptide are provided. Fusion proteins comprising a reverse transcriptase and a nucleic acid binding polypeptide are provided. Methods are provided for amplifying a nucleic acid sequence using a fusion protein comprising a nucleic acid binding polypeptide and a polymerase. Methods are provided for amplifying a nucleic acid sequence using a fusion protein comprising a nucleic acid binding polypeptide and a reverse transcriptase.
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