发明授权
US09265785B2 Compositions comprising decitabine and tetrahydrouridine and uses thereof
有权
包含地西他滨和四氢尿苷的组合物及其用途
- 专利标题： Compositions comprising decitabine and tetrahydrouridine and uses thereof
- 专利标题（中）： 包含地西他滨和四氢尿苷的组合物及其用途
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申请号： US13414546申请日： 2012-03-07
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公开(公告)号： US09265785B2公开(公告)日： 2016-02-23
- 发明人: Joseph Desimone , Yogen Saunthararajah
- 申请人： Joseph Desimone , Yogen Saunthararajah
- 申请人地址： US IL Urbana
- 专利权人： The Board of Trustees of the University of Illinois
- 当前专利权人： The Board of Trustees of the University of Illinois
- 当前专利权人地址： US IL Urbana
- 代理机构： Schwabe Williamson & Wyatt
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; A61K31/7072 ; A61K31/706
摘要：
Embodiments of compositions and methods for the treatment of blood disorders and malignancies in a subject are described herein. In one embodiment, a composition for the treatment of a blood disorder or a malignancy in a subject comprises decitabine, tetrahydrouridine, and an excipient. In another embodiment, a method for the treatment of a blood disorder or a malignancy in a subject comprises the oral administration of a composition comprising decitabine and tetrahydrouridine. In some examples, the composition may be administered 1-3 times weekly.
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