发明授权
US09248178B2 Different serotypes of vesicular stomatitis virus as expression vectors for immunization regimens
有权
不同血清型的水泡性口炎病毒作为免疫方案的表达载体
- 专利标题: Different serotypes of vesicular stomatitis virus as expression vectors for immunization regimens
- 专利标题(中): 不同血清型的水泡性口炎病毒作为免疫方案的表达载体
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申请号: US13376875申请日: 2010-06-08
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公开(公告)号: US09248178B2公开(公告)日: 2016-02-02
- 发明人: Chil-Yong Kang , Gyoung Nyoun Kim
- 申请人: Chil-Yong Kang , Gyoung Nyoun Kim
- 代理商 Eduardo Krupnik
- 国际申请: PCT/CA2010/000874 WO 20100608
- 国际公布: WO2010/142030 WO 20101216
- 主分类号: A61K39/12
- IPC分类号: A61K39/12 ; A61K39/205 ; C12N7/00 ; C12N15/86 ; A61K39/00
摘要:
Immunization platforms, immunization regimes and medicaments useful for inducing an immune response in a mammal and preventing or treating a pathogenic infection in a mammal, wherein said immunization platforms and medicaments comprise a recombinant vesicular stomatitis virus (VSV) of one serotype and a rVSV of another serotype and are used in a prime-boost immunization regime. In aspects of the invention one VSV serotype is Indiana and the other VSV serotype is New Jersey.
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