A wireless transceiver includes a transmit path configured to generate a radio frequency (RF) transmit signal for transmission via an antenna. A receive path is configured to receive an RF receive signal via the antenna. A circulator-based quadrature duplexer includes an in-phase circulator and a quadrature-phase circulator configured to couple the transmit signal from the transmit path to the antenna while generating a residual transmit signal on the receive path, and to couple the receive signal from the antenna to the receive path. The circulator-based quadrature duplexer promotes cancellation of the residual transmit signal on the receive path.