An image pickup apparatus including an image pickup device having a pixel section with a plurality of two-dimensionally arranged pixels and a frame memory which temporarily stores, in an analog manner, analog image data read out from the pixel section and first to third readout control sections which perform first readout control that reads out image data of all pixels obtained through one exposure from the pixel section and stores the image data in the frame memory and perform second readout control that nondestructively reads out a piece of image data of a smaller number of pixels than all the pixels from the image data of all the pixels stored in the frame memory a plurality of times such that the piece of image data each has different object region size.