Invention Grant
US09228016B2 Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
有权
抗糖皮质激素诱导的肿瘤坏死因子受体（GITR）的抗体及其用途
- Patent Title: Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
- Patent Title (中): 抗糖皮质激素诱导的肿瘤坏死因子受体（GITR）的抗体及其用途
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Application No.: US14732082Application Date: 2015-06-05
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Publication No.: US09228016B2Publication Date: 2016-01-05
- Inventor: Changyu Wang , Nils Lonberg , Alan J. Korman , Mark J. Selby , Mohan Srinivasan , Karla Henning , Michelle Minhua Han , Guodong Chen , Richard Huang , Indrani Chakraborty , Haichun Huang , Susan Wong , Huiming Li
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07H21/00 ; C07K16/28 ; A61K39/395 ; G01N33/68 ; G01N33/574 ; A61K39/00
Abstract:
Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
Public/Granted literature
- US20150353637A1 ANTIBODIES AGAINST GLUCOCORTICOID-INDUCED TUMOR NECROSIS FACTOR RECEPTOR (GITR) AND USES THEREOF Public/Granted day:2015-12-10
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