- 专利标题: Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
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申请号: US14543817申请日: 2014-11-17
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公开(公告)号: US09227963B2公开(公告)日: 2016-01-05
- 发明人: Le Wang , George Doherty , Xilu Wang , Zhi-Fu Tao , Milan Bruncko , Aaron R. Kunzer , Michael D. Wendt , Xiaohong Song , Robin Frey , Todd M. Hansen , Gerard M. Sullivan , Andrew Judd , Andrew J. Souers
- 申请人: AbbVie Inc.
- 申请人地址: US IL North Chicago
- 专利权人: ABBVIE INC.
- 当前专利权人: ABBVIE INC.
- 当前专利权人地址: US IL North Chicago
- 代理机构: Jones Day
- 主分类号: A61K31/535
- IPC分类号: A61K31/535 ; C07D417/14 ; C07D401/04 ; C07D471/04 ; C07D487/04 ; C07D493/08 ; C07D513/04
摘要:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
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