Invention Grant
- Patent Title: Methods for predictive automatic gain control for hybrid mass spectrometers
- Patent Title (中): 混合质谱仪预测自动增益控制方法
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Application No.: US14297092Application Date: 2014-06-05
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Publication No.: US09165755B2Publication Date: 2015-10-20
- Inventor: Philip M. Remes , Michael W. Senko , Justin Blethrow
- Applicant: Thermo Finnigan LLC
- Applicant Address: US CA San Jose
- Assignee: Thermo Finnigan LLC
- Current Assignee: Thermo Finnigan LLC
- Current Assignee Address: US CA San Jose
- Agent Thomas F. Cooney
- Main IPC: H01J49/00
- IPC: H01J49/00 ; H01J49/26 ; H01J49/42

Abstract:
A method for mass analyzing ions comprising a restricted range mass-to-charge (m/z) ratios comprising (i) performing a survey mass analysis, using a first mass analyzer employing indirect detection of ions by image current detection, to measure a flux of ions having m/z ratios within said range and (ii) performing a dependent mass analysis, using a second mass analyzer, of an optimal quantity of ions having m/z ratios within said range, said optimal quantity collected for a time period determined by the measured ion flux, the method characterized in that: the time period is determined using a corrected ion flux that includes a correction that comprises an estimate of the quantity of ions that are undetected by the first mass analyzer.
Public/Granted literature
- US20140361158A1 Methods for Predictive Automatic Gain Control for Hybrid Mass Spectrometers Public/Granted day:2014-12-11
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