发明授权
- 专利标题: Expression vector and methods of producing high levels of proteins
- 专利标题(中): 表达载体和产生高水平蛋白质的方法
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申请号: US11922548申请日: 2006-06-19
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公开(公告)号: US09163257B2公开(公告)日: 2015-10-20
- 发明人: Arun K. Singh , Ashish Goel , Sanjeev K. Mendiratta
- 申请人: Arun K. Singh , Ashish Goel , Sanjeev K. Mendiratta
- 申请人地址: IN Ahmedabad
- 专利权人: Cadila Healthcare Limited
- 当前专利权人: Cadila Healthcare Limited
- 当前专利权人地址: IN Ahmedabad
- 代理机构: Ladas & Parry LLP
- 优先权: IN720/MUM/2005 20050620
- 国际申请: PCT/IN2006/000207 WO 20060619
- 国际公布: WO2007/017903 WO 20070215
- 主分类号: C12N15/00
- IPC分类号: C12N15/00 ; C12N15/85 ; C07K14/715
摘要:
A process for high expression of protein of interest using an expression vector. The process comprises at least the following regulatory elements: a) a CMV promoter, or its functional variants, b) an intron, c) TPL or its functional variants, d) VA genes or functional variants, and e) a bovine growth hormone polyadenylation sequence or functional variants.
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